AHA Heart News

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Study Highlights:

  • Healthy nonsmokers experienced increased adrenaline levels in their heart after one electronic cigarette (e-cigarette) with nicotine.
  • The same healthy nonsmokers did not experience increased adrenaline levels in the heart after using one nicotine-free e-cigarette or a sham e-cigarette.
  • Acute e-cigarette use in nonsmokers did not appear to cause oxidative stress on the heart, but more studies are needed to confirm that finding.

Embargoed until 3 p.m. CT / 4 p.m. ET Wednesday, Sept. 20, 2017

DALLAS, Sept. 20, 2017 — Healthy nonsmokers may experience increased adrenaline levels in their heart after one electronic cigarette (e-cigarette) with nicotine, according to new research in Journal of the American Heart Association, the Open Access Journal of the American Heart Association/American Stroke Association.

Nerve endings in the sympathetic nervous system release both adrenaline (epinephrine) and noradrenalin (norepinephrine), both of which play a role in the fight or flight response. Perpetually increased activity of the sympathetic nervous system contributes to increased cardiac risk.

“While e-cigarettes typically deliver fewer carcinogens than are found in the tar of tobacco cigarette smoke, they also usually deliver nicotine. Many believe that the tar — not the nicotine — is what leads to increased cancer and heart attack risks,” said Holly R. Middlekauff, M.D., senior study author and professor of medicine (cardiology) and physiology at the David Geffen School of Medicine at UCLA. “So, we asked the question, are e-cigarettes safe?”

Middlekauff and her team used a technique called “heart rate variability” obtained from a prolonged, non-invasive heart rhythm recording. Heart rate variability is calculated from the degree of variability in the time between heart beats. This variability may be indicative of the amount of adrenaline on the heart.

Prior studies have used a heart rate variability test to link increased adrenaline activity in the heart with increased cardiac risk. People with known heart disease and people without known heart disease who have this pattern of high adrenaline levels in the heart have increased risk of death, Middlekauff said.

In what Middlekauff said is the first study to separate the nicotine from the non-nicotine components when looking at the heart impact of e-cigarettes on humans, researchers studied 33 healthy adults who were not current e-cigarette or tobacco cigarette smokers. On different days, each participant used an e-cigarette with nicotine, an e-cigarette without nicotine or a sham device. Researchers measured cardiac adrenaline activity by assessing heart rate variability, and oxidative stress in blood samples by measuring the enzyme plasma paraoxonase (PON1).

They found:

  • Exposure to e-cigarettes with nicotine, but not e-cigarettes without nicotine, led to increased adrenaline levels to the heart, as indicated by abnormal heart rate variability.

  • Oxidative stress, which increases risks for atherosclerosis and heart attack, showed no changes after exposure to e-cigarettes with and without nicotine. The number of markers they studied for oxidative stress were minimal, however and more studies are warranted, according to Middlekauff.

“While it’s reassuring that the non-nicotine components do not have an obvious effect on adrenaline levels to the heart, these findings challenge the concept that inhaled nicotine is benign, or safe. Our study showed that acute electronic cigarette use with nicotine increases cardiac adrenaline levels. And it’s in the same pattern that is associated with increased cardiac risk in patients who have known cardiac disease, and even in patients without known cardiac disease,” Middlekauff said. “I think that just seeing this pattern at all is very concerning and it would hopefully discourage nonsmokers from taking up electronic cigarettes.”

The American Heart Association believes that e-cigarettes, like all tobacco products, pose risk. The association supports FDA regulation of e-cigarettes that address marketing, youth access, characterizing flavors, free sampling, labeling, quality control over manufacturing and product standards for contaminants and other ingredients. The association also supports including e-cigarettes in comprehensive smoke-free air laws, taxation and comprehensive cessation programs.

Future studies should look more closely at oxidative stress and e-cigarette use, using a broader number of cardiac markers, in a larger population of people, researchers said.

Co-authors are Roya S. Moheimani, B.S.; May Bhetraratana, M.H.S.; Kacey M. Peters, B.S.; Benjamin K. Yang; Fen Yin, Ph.D.; Jeffrey Gornbein, Dr.PH; and Jesus A. Araujo, M.D., Ph.D. Author disclosures are on the manuscript.

The Tobacco-Related Disease Research Program; American Heart Association, Western States Affiliate; National Institute of Environmental Health Sciences, National Institutes of Health; Irma and Norman Switzer Dean's Leadership in Health and Science Scholarship; and UCLA Clinical and Translational Science Institute funded the study.

Additional Resources:

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Statements and conclusions of study authors published in American Heart Association scientific journals are solely those of the study authors and do not necessarily reflect the association’s policy or position. The association makes no representation or guarantee as to their accuracy or reliability. The association receives funding primarily from individuals; foundations and corporations (including pharmaceutical, device manufacturers and other companies) also make donations and fund specific association programs and events. The association has strict policies to prevent these relationships from influencing the science content. Revenues from pharmaceutical and device corporations and health insurance providers are available at www.heart.org/corporatefunding.

About the American Heart Association

The American Heart Association is devoted to saving people from heart disease and stroke – the two leading causes of death in the world. We team with millions of volunteers to fund innovative research, fight for stronger public health policies and provide lifesaving tools and information to prevent and treat these diseases. The Dallas-based association is the nation’s oldest and largest voluntary organization dedicated to fighting heart disease and stroke. To learn more or to get involved, call 1-800-AHA-USA1, visit heart.org or call any of our offices around the country. Follow us on Facebook and Twitter.

For Media Inquiries and AHA/ASA Spokesperson Perspective: 214-706-1173

Karen Astle: 214-706-1392; karen.astle@heart.org

For Public Inquiries: 1-800-AHA-USA1 (242-8721)

heart.org and strokeassociation.org

 

]]>Heart NewsWed, 20 Sep 2017 20:00:09 GMTStudy Highlights: Healthy nonsmokers experienced increased adrenaline levels in their heart after one electronic cigarette (e-cigarette) with nicotine. The same healthy nonsmokers did not experience increased adrenaline levels in the heart after using one nicotine-free e-cigarette or a sham e-cigarette. Acute e-cigarette use in nonsmokers did not appear to cause oxidative stress on the heart, but more studies are needed to confirm that finding. http://newsroom.heart.org/news/one-e-cigarette-may-lead-to-adrenaline-changes-in-nonsmokers-heartsWed, 20 Sep 2017 20:00:00 GMT
Embargoed 10:30 a.m. PT / 1:30 p.m. ET Sunday, Sept 17, 2017

SAN FRANCISCO, September 2017 — Organ damage from high blood pressure doesn’t only occur in adults; it can also happen in teenagers, according to research presented today at the American Heart Association (AHA) Council on Hypertension, AHA Council on Kidney in Cardiovascular Disease, American Society of Hypertension Joint Scientific Sessions 2017 in San Francisco.

And the damage to the heart and blood vessels can occur in youth at blood pressure levels that are below the clinical definition of hypertension in youth.

High blood pressure in youth is defined differently than it is in adults. In childhood, high blood pressure is based on percentiles, rather than blood pressure level. Researchers looked at whether organ damage in teens develops below the 95th percentile, which is the clinical definition of high blood pressure in youth.

Researchers studied blood pressure and measured organ damage in 180 teenagers (14-17 years old, 64 percent white, 57 percent males). They found evidence of organ damage even among the youth categorized as “normal” with blood pressure less than in the 80th percentile. They also found heart and vessel damage in the mid-risk group, which had blood pressures in the 80th to 90th percentiles and the high-risk group, with blood pressures above the 90th percentile.

“Some adolescents may have organ damage related to blood pressure and are not targeted for therapy,” said Elaine M. Urbina, M.D., M.S., study author and director of preventive cardiology at Cincinnati Children’s Hospital Medical Center in Ohio. “Imaging of the heart may be useful in youth in the high-normal range of blood pressure to determine how aggressive therapy should be.”

Additional Resources:

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Statements and conclusions of study authors that are presented at American Heart Association and American Stroke Association scientific meetings are solely those of the study authors and do not necessarily reflect association policy or position. The association makes no representation or warranty as to their accuracy or reliability. The association receives funding primarily from individuals; foundations and corporations (including pharmaceutical, device manufacturers and other companies) also make donations and fund specific association programs and events.  The association has strict policies to prevent these relationships from influencing the science content. Revenues from pharmaceutical and device corporations and health insurance providers are available at www.heart.org/corporatefunding.

 About the American Heart Association

The American Heart Association is devoted to saving people from heart disease and stroke – the two leading causes of death in the world. We team with millions of volunteers to fund innovative research, fight for stronger public health policies and provide lifesaving tools and information to prevent and treat these diseases. The Dallas-based association is the nation’s oldest and largest voluntary organization dedicated to fighting heart disease and stroke. To learn more or to get involved, call 1-800-AHA-USA1, visit heart.org or call any of our offices around the country. Follow us on Facebook and Twitter.

For Media Inquiries and AHA/ASA Spokesperson Perspective: 214-706-1173

Maggie Francis: 214-706-1382; maggie.francis@heart.org  

For Public Inquiries: 1-800-AHA-USA1 (242-8721)

heart.org and strokeassociation.org

]]>Heart NewsScientific Conferences & MeetingsStroke NewsSun, 17 Sep 2017 17:29:43 GMTHighlights: Organ damage from high blood pressure doesn’t only occur in adults; it can also happen in teenagers, according to research presented today at the American Heart Association (AHA) Council on Hypertension, AHA Council on Kidney in Cardiovascular Disease, American Society of Hypertension Joint Scientific Sessions 2017 in San Francisco.http://newsroom.heart.org/news/teens-also-at-risk-for-organ-damage-from-high-blood-pressureSun, 17 Sep 2017 17:30:00 GMT
SAN FRANCISCO, Sept. 16, 2017— Two leading hypertension researchers will be honored today at the American Heart Association’s Council on Hypertension, Council on Kidney in Cardiovascular Disease, and the American Society of Hypertension Joint Scientific Sessions in San Francisco.

This year’s recipients of the annual Excellence Award for Hypertension Research are Allyn L. Mark, M.D., professor of internal medicine-cardiovascular medicine, at the University of Iowa Carver College of Medicine, and Richard J. Roman, Ph.D., Billy S. Gutyon Distinguished Professor and Chair of pharmacology and toxicology at the University of Mississippi Medical Center. Both will present lectures on their work and receive their awards during a special dinner at the Scientific Sessions meeting.

Mark’s research has explored the roles of the brain and sympathetic nervous system in controlling blood pressure.

“Our research looked at two major contributors to hypertension: obesity and high salt intake,” Mark said. “We wanted to understand why some individuals are sensitive and other individuals are resistant to the hypertensive effects of high salt intake, as well as recognize the underlying causes of hypertension caused by obesity.”

Roman has devoted his career to studying how genes impact hypertension as well as determining patients’ susceptibility to kidney and brain damage. His team identified a gene that produces a compound called 20-HETE. This compound constricts blood vessels, and, in the kidney, it increases sodium excretion.

“Gene mutations that reduce 20-HETE can lead to hypertension and stroke in humans, and we have recently found that it also is associated with dementia in elderly patients.” Roman said. “This and other research lays the groundwork for much needed clinical trials looking at drugs that target 20-HETE for the treatment of stroke, heart attack and cancer.”

Established in 1966, the Excellence Award for Hypertension honors excellence in research and discoveries in the field of hypertension. Nominees are assessed by a committee on their impact in the field of hypertension throughout their careers, as well as any single discovery. All scientists with a background in hypertension research, and those who have made a meritorious scientific discovery or discoveries, either alone or with others, may be considered.

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About the American Heart Association

The American Heart Association is devoted to saving people from heart disease and stroke – the two leading causes of death in the world. We team with millions of volunteers to fund innovative research, fight for stronger public health policies and provide lifesaving tools and information to prevent and treat these diseases. The Dallas-based association is the nation’s oldest and largest voluntary organization dedicated to fighting heart disease and stroke. To learn more or to get involved, call 1-800-AHA-USA1, visit heart.org or call any of our offices around the country. Follow us on Facebook and Twitter.

For Media Inquiries: (214) 706-1382

AHA contact: maggie.francis@heart.org

For Public Inquiries: (800) AHA-USA1 (242-8721)

heart.org and strokeassociation.org

 

]]>Program NewsHeart NewsStroke NewsSun, 17 Sep 2017 15:13:11 GMTSAN FRANCISCO, Sept. 16, 2017— Two leading hypertension researchers will be honored today at the American Heart Association’s Council on Hypertension, Council on Kidney in Cardiovascular Disease, and the American Society of Hypertension Joint Scientific Sessions in San Francisco.http://newsroom.heart.org/news/american-heart-association-honors-scientists-for-excellence-in-groundbreaking-hypertension-researchSat, 16 Sep 2017 14:00:00 GMT
Study Highlights

  • Primary care practices using the Measure accurately, Act rapidly and Partner with patients (MAP) program drove down hypertension rates among patients.
  • In six months of MAP, hypertension control rose from 65.6 percent to 74.8 percent, among more than 21,000 hypertension patients at U.S. primary care practices.

Embargoed 3p.m. PT / 6p.m. ET, Saturday, Sept. 16, 2017

SAN FRANCISCO, Sept. 16, 2017— A quality improvement program designed to better control hypertension in primary care practices notably improved hypertension control in six months, according to research presented today at the American Heart Association (AHA) Council on Hypertension, AHA Council on Kidney in Cardiovascular Disease, American Society of Hypertension Joint Scientific Sessions 2017, in San Francisco.

One in three American adults has high blood pressure. That number is steadily climbing, despite the fact that high blood pressure can be easily treated using evidence-based guidelines.

Based on the American Medical Association’s M.A.P. Framework, the AMA collaborated with Care Coordination Institute Labs, Greenville South Carolina, to create the M.A.P. hypertension improvement program using the latest science in blood pressure control. It stands for measuring blood pressure accurately; acting rapidly to manage uncontrolled blood pressure; and partnering with patients to promote blood pressure self-management.

“The goal of the M.A.P. is to make it easier for doctors and care teams to help people with hypertension effectively manage their blood pressure,” said study author Michael Rakotz, M.D., vice president of chronic disease prevention at the American Medical Association (AMA), based in Chicago.

Researchers compared blood pressure measurements of more than 21,000 hypertensive patients from 16 practices, comparing their blood pressures from the start of the study to those taken six months into participating in the MAP intervention.

They found:

  • Blood pressure control rose from 65.6 percent to 74.8 percent in six months.
  • Twelve of the 16 practices in the study reported notably better blood pressure control in their hypertensive patients.
  • Among the uncontrolled patients at the study’s start, average blood pressure fell from 149/85 to 139/80 mm Hg.
  • Teaching accurate blood pressure measurement technique resulted in reduced systolic pressures in uncontrolled patients in the office.
  • There was no notable change in physicians increasing the number of or dosage of anti-hypertensive medications to treat patients with uncontrolled blood pressure.
  • There was a significant increase in drop in blood pressure with each medication change made during the study (14 mm Hg), compared to drops in blood pressure with each medication change prior to the study (5.4 mm Hg), implying that either patients are doing better at taking their medications daily or that the medications they are being prescribed are working better, according to Rakotz.

“MAP’s evidence-based strategies offer an opportunity for primary care practices to work with patients to quickly improve blood pressure control. And the initiative goes hand-in-hand with national programs focused on reducing the burden of heart disease and stroke, including Target: BP,” Rakotz said.

Target: BP™ is a joint initiative between the AHA and AMA aimed at reducing the number of American adults who die each year from heart attack and stroke. The MAP BP improvement program is a central part of the initiative.  

High blood pressure contributes to major health problems, including heart attack, heart failure, stroke, kidney failure and more. The American Heart Association’s goal is to improve cardiovascular health of all Americans by 20 percent while reducing deaths from cardiovascular disease and stroke by 20 percent by the year.

Co-authors are Brent Egan, M.D.; R. Bruce Hanin, M.D.; Irfan Asif, M.D., Jianing Yang, M.S., Susan Sutherland, Ph.D., Robert Davis; and Gregory Wozniak, Ph.D.

Author disclosures are on the manuscript.

The American Medical Association funded this study.

Note: Scientific presentation time of abstract 93 is 4:30 p.m. PT/ 7:30 p.m. ET, Saturday, Sept. 16, 2017.

Additional Resources:

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Statements and conclusions of study authors that are presented at American Heart Association and American Stroke Association scientific meetings are solely those of the study authors and do not necessarily reflect association policy or position. The association makes no representation or warranty as to their accuracy or reliability. The association receives funding primarily from individuals; foundations and corporations (including pharmaceutical, device manufacturers and other companies) also make donations and fund specific association programs and events.  The association has strict policies to prevent these relationships from influencing the science content. Revenues from pharmaceutical and device corporations and health insurance providers are available at www.heart.org/corporatefunding.

About the American Heart Association

The American Heart Association is devoted to saving people from heart disease and stroke – the two leading causes of death in the world. We team with millions of volunteers to fund innovative research, fight for stronger public health policies and provide lifesaving tools and information to prevent and treat these diseases. The Dallas-based association is the nation’s oldest and largest voluntary organization dedicated to fighting heart disease and stroke. To learn more or to get involved, call 1-800-AHA-USA1, visit heart.org or call any of our offices around the country. Follow us on Facebook and Twitter.

For Media Inquiries and AHA/ASA Spokesperson Perspective: 214-706-1173

Maggie Francis: 214-706-1382; maggie.francis@heart.org 

For Public Inquiries: 1-800-AHA-USA1 (242-8721)

heart.org and strokeassociation.org

 

]]>Heart NewsScientific Conferences & MeetingsStroke NewsSat, 16 Sep 2017 22:00:18 GMTStudy Highlights: Primary care practices using the Measure accurately, Act rapidly and Partner with patients (MAP) program drove down hypertension rates among patients. In six months of MAP, hypertension control rose from 65.6 percent to 74.8 percent, among more than 21,000 hypertension patients at U.S. primary care practices. http://newsroom.heart.org/news/blood-pressure-better-controlled-with-map-for-doctorsSat, 16 Sep 2017 22:00:00 GMT
Study Highlight:

  • Overall, home blood pressure monitoring has increased among U.S. adults.
  • However, those with less than a high school diploma and no partner are less likely to monitor blood pressure at home.
  • Adults who have and are being treated for high blood pressure show higher rates of home monitoring.

Embargoed until 11:45a.m. PT/ 2:45p.m. ET, Saturday, Sept. 16

SAN FRANCISCO, Sept. 16, 2017 – Having a lower education level and no partner is associated with a lower frequency of home blood pressure monitoring, according to new research presented at the American Heart Association’s Council on Hypertension 2017 Scientific Sessions.

Researchers assessed the data of 6,113 U.S. adults from the 2013-2014 National Health and Nutrition Examination Survey (NHANES).

They found:

  • The number of American adults checking blood pressure at home at least monthly has increased about 4 percent (from 21.7 percent in 2009-2010 to 25.5 percent in 2013-2014).
  • Having less than a high school diploma and no partner was associated with a lower frequency of home blood pressure monitoring.
  • Adults who had high blood pressure, were aware of high blood pressure and were being treated for high blood pressure showed higher rates of home monitoring.

The American Heart Association recommends home monitoring for all people with high blood pressure. Home monitoring allows hypertensive individuals to take ownership of their treatment and helps healthcare providers determine whether treatments are working. It also helps to evaluate potential false readings that differ between the doctor’s office and at home.

This recommendation is in concert with the American Heart Association and American Medical Association’s nationwide initiative, Target: BP, which encourages health care providers to reach and sustain a blood pressure control rate of 70 percent or higher among their patients.

Co-authors include Joel C. Marrs, Pharm.D.; Sarah L. Anderson, Pharm.D.

Additional Resources:

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Statements and conclusions of study authors that are presented at American Heart Association scientific meetings are solely those of the study authors and do not necessarily reflect association policy or position. The association makes no representation or warranty as to their accuracy or reliability. The association receives funding primarily from individuals; foundations and corporations (including pharmaceutical, device manufacturers and other companies) also make donations and fund specific association programs and events. The association has strict policies to prevent these relationships from influencing the science content. Revenues from pharmaceutical and device corporations are available at www.heart.org/corporatefunding.

For Media Inquiries and AHA/ASA Spokesperson Perspective: 214-706-1173

Maggie Francis: 214-706-1382; maggie.francis@heart.org 

For Public Inquiries: 1-800-AHA-USA1 (242-8721)

heart.org and strokeassociation.org

 

]]>Heart NewsScientific Conferences & MeetingsStroke NewsSat, 16 Sep 2017 18:47:43 GMTStudy Highlight: Overall, home blood pressure monitoring has increased among U.S. adults. However, those with less than a high school diploma and no partner are less likely to monitor blood pressure at home. Adults who have and are being treated for high blood pressure show higher rates of home monitoring. http://newsroom.heart.org/news/adults-without-partners-monitor-their-blood-pressure-less-frequentlySat, 16 Sep 2017 18:45:00 GMT
Heart NewsScientific Conferences & MeetingsStroke NewsFri, 15 Sep 2017 22:00:09 GMTStudy Highlights: Gender matters when it comes to what’s most likely to elevate blood pressure in young to middle-aged adults. The volume of blood pumped from the left ventricle during heartbeats, i.e., stroke volume, is the main determinant of blood pressure levels in women, while blood pressure in men is more likely to be determined by the amount of resistance in the body’s blood vessels. The results suggest a possible need for gender-specific treatment of high blood pressure in young to middle-aged people. http://newsroom.heart.org/news/high-blood-pressure-reasons-differ-by-gender-in-teens-young-adultsFri, 15 Sep 2017 22:00:00 GMT
Aspectos destacados:

  • Las mujeres que desarrollan preeclampsia temprano en el embarazo son más propensas que las mujeres sin este síndrome a sufrir un engrosamiento del músculo cardíaco izquierdo un mes después del parto.
  • Los cambios del músculo cardíaco fueron más graves entre las mujeres que desarrollaron preeclampsia antes de las 34 semanas de embarazo.
  • En otro estudio, la monitorización de telemedicina parece prometedora para reducir los reingresos hospitalarios de mujeres que desarrollan hipertensión justo después de dar a luz.

Prohibida su publicación hasta las 15:00 PT/18:00 ET del jueves, 14 de septiembre de 2017

SAN FRANCISCO, 14, de septiembre de 2017 – Las mujeres que desarrollan preeclampsia temprano en el embarazo son más propensas a sufrir un engrosamiento del músculo cardíaco izquierdo un mes después del parto. Los cambios fueron más graves entre las mujeres de desarrollaron el síndrome pronto, después de la semana 34 del embarazo, de acuerdo con las investigaciones presentadas hoy en las sesiones científicas en conjunto de 2017 del Council on Hypertension de la American Heart Association (AHA), el Council on Kidney in Cardiovascular Disease de la AHA, la American Society of Hypertension en San Francisco.

La preeclampsia es una peligrosa elevación de la presión arterial que se produce en la segunda mitad del embarazo. Las mujeres con preeclampsia suelen tener una cantidad anormal de proteínas en la orina. De acuerdo con los National Institutes of Health, el número exacto de mujeres que desarrollan preeclampsia no se conoce pero se estima que está entre un 2% y un 8% de todos los embarazos en todo el mundo y alrededor de un 3,4% en Estados Unidos.

La aparición temprana de la preeclampsia, que ocurre antes de la semana 34 de gestación, normalmente es una forma más grave de la enfermedad, declaró el autor del estudio, el Dr. GianLuca Colussi, profesor adjunto de medicina en la Universidad de Udine en Udine, Italia. "Las mujeres con preeclampsia de aparición temprana tienen el mayor riesgo de desarrollar una enfermedad cardiovascular posteriormente."

Colussi y sus compañeros estudiaron la estructura del corazón y su función en 65 mujeres un mes después del parto. Las mujeres no tenían la presión arterial alta antes de quedarse embarazadas pero desarrollaron preeclampsia durante el embarazo. Un treinta y seis por cierto de estas mujeres sufrió una preeclampsia de aparición temprana. Para realizar comparaciones, también incluyeron en el estudio a 16 mujeres no embarazadas con hipertensión, 6 mujeres embarazadas sanas y 30 mujeres no embarazadas sanas.

Esto fue lo que descubrieron:

  • En comparación con las mujeres sanas embarazadas y no embarazadas, las mujeres con preeclampsia presentaban un mayor riesgo de hipertrofia del ventrículo izquierdo. Esto sucede cuando la cavidad de bombeo izquierda del corazón se engrosa, lo que dificulta que el corazón bombee de forma eficiente.

  • Las mujeres con preeclampsia también eran más propensas a sufrir cambios en el ventrículo izquierdo lo que se traduce en una disfunción diastólica, que pone en peligro la capacidad del corazón para relajarse y llenarse de sangre.

  • Las mujeres con preeclampsia de aparición temprana desarrollaron cambios del ventrículo izquierdo más graves, muy similares a los que se suelen observar en pacientes con hipertensión crónica con un alto riesgo de trastornos cardiovasculares.

  • Entre las mujeres con preeclampsia, las que tuvieron la de aparición tardía tenían niveles de presión arterial más altos, una media de 136/91 mm Hg, que aquellas con una aparición temprana, con una media de 125/87 mm Hg. Una posible explicación, según Colussi, puede ser que las pacientes con preeclampsia de aparición temprana se recuperaron antes que las pacientes con preeclampsia de aparición tardía después del parto.

Los hallazgos señalan que las mujeres embarazadas con preeclampsia y sus médicos deben ser conscientes del elevado riesgo cardiovascular que puede ocurrir después del parto.

"Se deben realizar cribados a estas mujeres para detectar factores de riesgo cardiovascular importantes y deben implementarse estrategias de prevención tan pronto como sea posible", afirmó Colussi. "Hemos demostrado que las mujeres preeclampsia de aparición temprana podrían tener un riesgo incluso mayor, por lo que se recomiendan intervenciones preventivas, como el uso de fármacos que actúan en el remodelado del ventrículo izquierdo."

"Se necesitan más investigaciones con más pacientes para validar estos resultados, así como para ayudar a explicar por qué los cambios en el corazón son más propensos a ocurrir", afirmó.

En otro estudio sobre la preeclampsia presentado en la reunión científica (resumen 34), los investigadores evaluaron una intervención de tratamiento y monitorización con telemedicina, para mujeres con presión arterial alta grave después del parto o con riesgo de desarrollarla. Los primeros resultados sugieren que el enfoque es factible, las pacientes lo aceptan y es una estrategia prometedora para reducir los reingresos hospitalarios y las complicaciones relacionadas con la hipertensión posparto.

Coautores con Colussi son la Dra. Cristiana Catena, Ph.D.; Dra. Lorenza Driul; Dra. Francesca Pezzutto; Dra. Valentina Fagotto; y Dr. Leonardo Alberto Sechi. Los conflictos de interés de los autores están en el artículo. La PierSilverio Nassimbeni Foundation ha financiado el estudio del Dr. Colussi.

Los coautores del estudio de telemonitorización son Kara K. Hoppe, Julie B. Zella, Nicole A. Thomas, Heather M. Johnson.

Nota: La hora de presentación para los resúmenes 26 y 34 es 15:20 PT/18:20 ET, jueves, 14 de septiembre de 2017

Recursos adicionales:

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Las declaraciones y conclusiones de los autores de los estudios que se presentan en las reuniones científicas de la American Heart Association y la American Stroke Association pertenecen a los autores del estudio y no reflejan necesariamente la postura ni las políticas de la asociación. La asociación no ofrece garantía de ningún tipo de su exactitud o fiabilidad. La asociación recibe financiación de personas particulares principalmente; también realizan donaciones fundaciones y empresas (incluidas empresas farmacéuticas y fabricantes de dispositivos entre otras) y financian eventos o programas específicos de la asociación. La asociación tiene políticas estrictas para evitar que estas relaciones influyan en el contenido científico. Los ingresos procedentes de empresas famacéuticas y fabricantes de dispositivos así como de proveedores de seguros sanitarios están disponibles en www.heart.org/corporatefunding

Acerca de la American Heart Association

La American Heart Association está comprometida con la prevención de las cardiopatías y los accidentes cerebrovasculares, las dos causas principales de muerte en el mundo. Nuestro equipo está formado por millones de voluntarios para financiar la investigación innovadora, luchar por una política de sanidad pública más fuerte y proporcionar herramientas e información que salvan vidas para evitar y tratar estas enfermedades. La asociación tiene su sede en Dallas y es la organización formada por voluntarios mayor y más antigua del país dedicada a luchar contra las cardiopatías y los accidentes cerebrovasculares. Para obtener más información o implicarse en la causa, llame al 1-800-AHA-USA1, visite heart.org o llame a cualquiera de nuestras oficinas situadas por todo el país. Síganos en Facebook y Twitter.

Para consultas de los medios de comunicación y el punto de vista de la portavoz de la AHA/ASA: 214-706-1173

Maggie Francis: 214-706-1382; maggie.francis@heart.org

Para consultas públicas: 1-800-AHA-USA1 (242-8721)

heart.org y strokeassociation.org

]]>Heart NewsForeign Language News ReleasesStroke NewsThu, 14 Sep 2017 22:07:01 GMTAspectos destacados: Las mujeres que desarrollan preeclampsia temprano en el embarazo son más propensas que las mujeres sin este síndrome a sufrir un engrosamiento del músculo cardíaco izquierdo un mes después del parto. Los cambios del músculo cardíaco fueron más graves entre las mujeres que desarrollaron preeclampsia antes de las 34 semanas de embarazo. En otro estudio, la monitorización de telemedicina parece prometedora para reducir los reingresos hospitalarios de mujeres que desarrollan hipertensión justo después de dar a luz. http://newsroom.heart.org/news/es-posible-que-las-mujeres-con-complicaciones-en-el-embarazo-tengan-la-funcion-cardiaca-afectada-despues-del-partoThu, 14 Sep 2017 22:00:00 GMT
Aspectos destacados del estudio:

  • Mantener un peso saludable supone un aspecto clave para prevenir aumentos de la presión arterial desde la juventud hasta la madurez.
  • Estos hallazgos apoyan la necesidad de crear intervenciones que ayuden a las personas a mantener un peso normal durante toda la vida.

Prohibida su publicación hasta las 15:00 PT / 18:00 ET del jueves 14 de septiembre de 2017

SAN FRANCISCO, 14 de septiembre de 2017 – Nuevas investigaciones demuestran que mantener un peso saludable durante toda la vida – incluso más que los otros factores estudiados – es importante para controlar la presión arterial, de acuerdo con las investigaciones presentadas hoy en las sesiones científicas conjuntas de 2017 del Council on Hypertension de la American Heart Association (AHA), el Council on Kidney in Cardiovascular Disease de la AHA, la American Society of Hypertension en San Francisco.

“El aumento de la presión arterial en edades jóvenes está asociado a la aparición temprana de cardiopatías y accidentes cerebrovasculares; las directrices estadounidenses para el tratamiento de la hipertensión alientan que se mantengan hábitos saludables durante toda la vida para limitar los aumentos de la presión arterial”, ha manifestado John N. Booth III, Ph.D., investigador posdoctoral de la Strategically Focused Hypertension Research Network de la American Heart Association en la Universidad de Alabama en Birmingham (EE. UU.). “Estudiamos específicamente el impacto a largo plazo de mantener hábitos saludables sobre los cambios de la presión arterial entre el periodo de juventud y de madurez”.

Los investigadores analizaron el impacto de mantener cinco hábitos saludables sobre los niveles de presión arterial durante 25 años:

  • Un peso saludable, definido como índice de masa corporal inferior a 25 kg/m2.
  • No fumar nunca.
  • De 0 a 7 bebidas alcohólicas a la semana para las mujeres y de 0 a 14 para los hombres.
  • 150 minutos o más de actividad física, de moderada a intensa, a la semana.
  • Mantener una dieta sana, basada en el plan dietético Dietary Approaches to Stop Hypertension (enfoques dietéticos para detener la hipertensión).

Se evaluaron 4.630 participantes del estudio "Coronary Artery Risk Development in Young Adults" (Desarrollo de riesgo en arterias coronarias en jóvenes adultos), que tenían de de 18 a 30 años en 1985 y 1986, cuando comenzó el estudio. Durante el seguimiento de 25 años, los investigadores midieron la presión arterial y los hábitos saludables 8 veces, hasta que los participantes alcanzaron la madurez.

Esto fue lo que descubrieron:

  • Los participantes que mantuvieron un peso saludable tenían más probabilidades de tener presión arterial normal conforme cumplían años. En concreto, aquellos que mantuvieron un peso óptimo tenían un 41% menos de probabilidad de elevar la presión arterial conforme cumplían años.
  • Practicar actividad física o mantener una dieta saludable no estaban asociadas a cambios en la presión arterial durante el periodo de 25 años.
  • No fumar nunca y no consumir alcohol o un consumo moderado se asociaron a un menor aumento en la presión arterial en la madurez, pero se requiere un estudio mayor para verificar esta relación.
  • Los participantes en el estudio que mantuvieron al menos 4 de los hábitos tenían un 27% más de posibilidades de tener presión arterial normal que un aumento de la presión arterial desde la juventud a la madures.

“Estos datos sugieren que el peso es un factor muy importante para mantener una presión arterial normal desde la juventud hasta la madures”, señaló el Dr. Booth. “Estos resultados aportan pruebas de que lo que debemos hacer es centrarnos en cómo crear intervenciones que permitan a las personas mantener un peso normal durante toda la vida. Los demás hábitos estudiados pueden jugar un papel importante, ya que pueden influir en el peso corporal”.

Además, aunque no estaban tan estrechamente relacionados con los cambios en la presión arterial con el tiempo, el Dr. Booth enfatizó que los otros hábitos saludables aportan claros beneficios para la salud cardiovascular general y ayudan a mantener un buen peso. “La American Heart Association recomienda mantener hábitos saludables para evitar factores de riesgo de desarrollo de cardiopatías y accidentes cerebrovasculares, incluida la hipertensión arterial”.

Los coautores son Norrina B. Allen, Ph.D.; April P. Carson, Ph.D.; David Calhoun, M.D.; Daichi Shimbo, M.D.; James M. Shikany, Dr.Ph.; Cora E. Lewis, M.D.; David T. Redden, Ph.D. y Paul Muntner, Ph.D. Los conflictos de interés de los autores están en el artículo.

El National Heart Lung and Blood Institute de los National Institutes of Health y la American Heart Association han financiado este estudio.

Nota: La hora de presentación científica del póster P149 es  las 17:30 PT/ 20:30. ET del jueves 14 de septiembre de 2017.

Recursos adicionales:

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Las declaraciones y conclusiones de los autores de los estudios que se presentan en las reuniones científicas de la American Heart Association y la American Stroke Association pertenecen a los autores del estudio y no reflejan necesariamente la postura ni las políticas de la asociación. La asociación no ofrece garantía de ningún tipo de su exactitud o fiabilidad. La asociación recibe financiación de personas particulares principalmente; también realizan donaciones fundaciones y empresas (incluidas empresas farmacéuticas y fabricantes de dispositivos entre otras) y financian eventos o programas específicos de la asociación. La asociación tiene políticas estrictas para evitar que estas relaciones influyan en el contenido científico. Los ingresos procedentes de empresas famacéuticas y fabricantes de dispositivos así como de proveedores de seguros sanitarios están disponibles en www.heart.org/corporatefunding.

Acerca de la American Heart Association

La American Heart Association está comprometida con la prevención de las cardiopatías y los accidentes cerebrovasculares, las dos causas principales de muerte en el mundo. Nuestro equipo está formado por millones de voluntarios para financiar la investigación innovadora, luchar por una política de sanidad pública más fuerte y proporcionar herramientas e información que salvan vidas para evitar y tratar estas enfermedades. La asociación tiene su sede en Dallas y es la organización formada por voluntarios mayor y más antigua del país dedicada a luchar contra las cardiopatías y los accidentes cerebrovasculares. Para obtener más información o implicarse en la causa, llame al 1-800-AHA-USA1, visite heart.org o llame a cualquiera de nuestras oficinas situadas por todo el país. Síganos en Facebook y Twitter.

Para consultas de los medios de comunicación y el punto de vista de la portavoz de la AHA/ASA: 214-706-1173

Maggie Francis: 214-706-1382; maggie.francis@heart.org.

Para consultas públicas: 1-800-AHA-USA1 (242-8721)

heart.org y strokeassociation.org

]]>Heart NewsForeign Language News ReleasesStroke NewsThu, 14 Sep 2017 22:07:43 GMTAspectos destacados del estudio: Mantener un peso saludable supone un aspecto clave para prevenir aumentos de la presión arterial desde la juventud hasta la madurez. Estos hallazgos apoyan la necesidad de crear intervenciones que ayuden a las personas a mantener un peso normal durante toda la vida. http://newsroom.heart.org/news/mantener-un-peso-saludable-ayuda-a-tener-una-baja-presion-arterial-durante-toda-la-vidaThu, 14 Sep 2017 22:00:00 GMT
Heart NewsScientific Conferences & MeetingsStroke NewsThu, 14 Sep 2017 22:00:14 GMTHighlights: Women who develop preeclampsia in earlier pregnancy are more likely than women without the condition to have thickening of the left heart muscle one month after delivery. The heart muscle changes were more severe among women who developed preeclampsia before 34 weeks of pregnancy. In another study, telehealth monitoring shows promise to reduce hospital readmissions in women who develop hypertension immediately after having a baby. http://newsroom.heart.org/news/women-with-pregnancy-complication-may-have-impaired-heart-function-after-deliveryThu, 14 Sep 2017 22:00:00 GMT
Heart NewsScientific Conferences & MeetingsStroke NewsThu, 14 Sep 2017 22:00:08 GMTStudy Highlights: Maintaining a healthy weight is a key health behavior to prevent blood pressure increases from young adulthood into middle age. These findings support the need to create interventions that will help people maintain normal body weight throughout their lives. http://newsroom.heart.org/news/maintaining-healthy-weight-helps-keep-blood-pressure-low-through-lifeThu, 14 Sep 2017 22:00:00 GMT
Study Highlight:

  • Cardiovascular disease risk is higher in people with low income or who live in low income neighborhoods regardless of their access to healthy food.

Embargoed until 3 p.m. CT / 4 p.m. ET, Wednesday, September 13, 2017

DALLAS, Sept. 13, 2017 – The risk for developing cardiovascular disease is higher in individuals living in low income neighborhoods or with lower personal income regardless of their access to healthy food, according to new research published in Circulation: Cardiovascular Quality and Outcomes, an American Heart Association journal.

The study, conducted by Emory University School of Medicine, focused on the effects of income, education and socioeconomic status on healthy people living in urban food deserts in the Atlanta metropolitan area. A food desert is defined by the United States Department of Agriculture (USDA) as a location with both low access to healthy food and low income. Areas with low access to healthy foods are defined as areas where a significant share of people live a mile or more away in urban areas or 10 miles or more away in rural areas from a supermarket, supercenter or large grocery store. The USDA estimates 23.5 million people live in food deserts across the United States.

The researchers analyzed data from 1,421 subjects who were recruited into two health studies: 712 from the META-Health (Morehouse and Emory Team up to Eliminate Health Disparities) study and 709 from the Predictive Health study, which recruited university employees from Emory University and the Georgia Institute of Technology. Participants were 20 to 70 years old with an average age of 49.4 years, 38.5 percent were male and 36.6 percent were Black. 

The researchers studied demographic data, metabolic profiles and early signs of cardiovascular disease, including markers for inflammation and stiffness of the arteries, an early indicator of blood vessel disease. The researchers found that people living in food deserts (13.2 percent) had higher rates of smoking, a higher prevalence of high blood pressure and higher body mass index as well as increased arterial stiffness compared to those not living in food deserts.

The researchers then analyzed these risk factors with respect to the average neighborhood income and individual income. People living in food deserts in low income areas had no significant difference in the studied markers for heart disease compared to people living in areas with low income and good food access. People with high individual income who lived in low income areas had lower cardiovascular risk and inflammation compared to people with lower individual income who lived in a similar area. Moreover, people with high individual income who lived in an area with poor food access had a better cardiovascular profile than those with lower individual income who lived in similar area. 

Overall, personal income appeared to be the most important driver of cardiovascular disease risk.

According to the researchers, one of the study’s limitations is that it only measured risk factors and early blood vessel disease. These factors increase the risk for cardiovascular disease. In order to confirm that low income contributes to early heart disease or higher mortality from heart disease, a study with a larger number of participants with much longer follow-up needs to be conducted.

“At least in the urban environment, the definition of a food desert wasn't sufficient to explain poor health in terms of cardiovascular risk factors,” said senior author Arshed A. Quyyumi, M.D., FACC, FRCP, a professor of medicine at Emory University School of Medicine and co-director of the Emory Clinical Cardiovascular Research Institute. “This study shows that low personal income and low socioeconomic status matter when it comes to cardiovascular disease risk. Physicians need to be aware that these social determinants increase disease risk and that perhaps more attention needs to be paid to patients who fall into this category.”

Co-authors are Heval M. Kelli, M.D.; Muhammad Hammadah, M.D.; Hina Ahmed, MPH; Yi-An Ko, Ph.D.; Matthew Topel, M.D., M.Sc.; Ayman Samman-Tahhan, M.D.; Mossab Awad, M.D.; Keyur Patel, M.D.; Kareem Mohammed, M.D.; Laurence S. Sperling, M.D.; Priscilla Pemu, M.D.; Viola Vaccarino, M.D., Ph.D.; Tene Lewis, Ph.D.; Herman Taylor, M.D., MPH; Greg Martin, M.D., M.Sc.; and Gary H. Gibbons, M.D. Author disclosures are on the manuscript.

The National Heart, Blood, and Lung Institute; the National Center for Research Resources; the National Center for Advancing Translational Sciences; and the Marcus, Robert W. Woodruff, and Abraham J. and Phyllis Katz Foundations funded the study.

Additional Resources:

For more information on healthy foods visit:

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Statements and conclusions of study authors published in American Heart Association scientific journals are solely those of the study authors and do not necessarily reflect the association’s policy or position. The association makes no representation or guarantee as to their accuracy or reliability. The association receives funding primarily from individuals; foundations and corporations (including pharmaceutical, device manufacturers and other companies) also make donations and fund specific association programs and events. The association has strict policies to prevent these relationships from influencing the science content. Revenues from pharmaceutical and device corporations and health insurance providers are available at www.heart.org/corporatefunding

About the American Heart Association

The American Heart Association is devoted to saving people from heart disease and stroke – the two leading causes of death in the world. We team with millions of volunteers to fund innovative research, fight for stronger public health policies and provide lifesaving tools and information to prevent and treat these diseases. The Dallas-based association is the nation’s oldest and largest voluntary organization dedicated to fighting heart disease and stroke. To learn more or to get involved, call 1-800-AHA-USA1, visit heart.org or call any of our offices around the country. Follow us on Facebook and Twitter.

For Media Inquiries and AHA/ASA Spokesperson Perspective: 214-706-1173

Carrie Thacker: 214-706-1665; carrie.thacker@heart.org

For Public Inquiries: 1-800-AHA-USA1 (242-8721)

heart.org and strokeassociation.org

]]>Heart NewsWed, 13 Sep 2017 20:00:09 GMTStudy Highlight: Cardiovascular disease risk is higher in people with low income or who live in low income neighborhoods regardless of their access to healthy food. http://newsroom.heart.org/news/risk-of-heart-disease-in-urban-food-deserts-is-associated-with-individual-s-income-rather-than-access-to-healthy-foodWed, 13 Sep 2017 20:00:00 GMT
DALLAS, TX September 12, 2017 — The American Heart Association, the world’s leading voluntary health organization devoted to fighting cardiovascular disease and stroke, applauds today’s announcement from Dr. Tom Frieden, Vital Strategies, Bloomberg Philanthropies, the Chan Zuckerberg Initiative and the Bill & Melinda Gates Foundation in creating Resolve to Save Lives, an initiative leveraging the strengths and resources of these partners to invest in public health strategies to save lives in low- and middle-income countries.

“In our work in more than 70 countries and with thousands of hospitals around the world, we have seen the need for improving the public health infrastructure and surveillance systems to decrease preventable diseases and deaths,” said American Heart Association CEO Nancy Brown. “Dr. Frieden’s global leadership is urgently needed and compliments our own efforts to increase control of blood pressure, reduce dietary sodium intake, eliminate trans fats and ensure every nation has the needed systems in place to help their communities build healthier lives, free of cardiovascular diseases and stroke. The launch of the Resolve initiative has the potential to not just transform public health, but to transform nations. The American Heart Association looks forward to working with this groundbreaking global health initiative as part of our growing worldwide outreach.”

The American Heart Association has valued our longstanding relationship with Dr. Tom Frieden. Our successful collaborations include incentivizing the food and restaurant industries to provide healthier options by reducing sodium and eliminating trans fats, tobacco control and the Million Hearts initiative. This new global project provides additional opportunities to save 100 million lives from heart disease and stroke.

###

About the American Heart Association

The American Heart Association is devoted to saving people from heart disease and stroke – the two leading causes of death in the world. We team with millions of volunteers to fund innovative research, fight for stronger public health policies and provide lifesaving tools and information to prevent and treat these diseases. The Dallas-based association is the nation’s oldest and largest voluntary organization dedicated to fighting heart disease and stroke. To learn more or to get involved, call 1-800-AHA-USA1, visit heart.org or call any of our offices around the country. Follow us on Facebook and Twitter.

About the American Stroke Association

The American Stroke Association is devoted to saving people from stroke — the No. 2 cause of death in the world and a leading cause of serious disability. We team with millions of volunteers to fund innovative research, fight for stronger public health policies and provide lifesaving tools and information to prevent and treat stroke. The Dallas-based association officially launched in 1998 as a division of the American Heart Association. To learn more or to get involved, call 1-888-4STROKE or visit StrokeAssociation.org. Follow us on Facebook and Twitter.

The American Heart Association/American Stroke Association receives funding mostly from individuals. Foundations and corporations donate as well, and fund specific programs and events. Strict policies are enforced to prevent these relationships from influencing the Association's science content. Financial information for the American Heart Association, including a list of contributions from pharmaceutical companies and device manufacturers, is available at http://www.heart.org/corporatefunding.

For Media Inquiries: (214) 706-1173

Suzette.Harris@heart.org, (214) 706-1207

For Public Inquiries: (800) AHA-USA1 (242-8721)

heart.org and strokeassociation.org

 

]]>Advisories & CommentsHeart NewsStroke NewsTue, 12 Sep 2017 16:09:37 GMTDALLAS, TX September 12, 2017 — The American Heart Association, the world’s leading voluntary health organization devoted to fighting cardiovascular disease and stroke, applauds today’s announcement from Dr. Tom Frieden, Vital Strategies, Bloomberg Philanthropies, the Chan Zuckerberg Initiative and the Bill & Melinda Gates Foundation in creating Resolve to Save Lives, an initiative leveraging the strengths and resources of these partners to invest in public health strategies to save lives in low- and middle-income countries.http://newsroom.heart.org/news/global-health-initiative-could-transform-nationsTue, 12 Sep 2017 15:37:00 GMT
Study Highlights

  • Black teens who lived through the Great Recession of 2007-2009 may have higher risk of metabolic syndrome, a cluster of several heart disease and diabetes risk factors.
  • Black teens whose families were already in poverty when the Great Recession hit and became more deeply impoverished during that time were at highest risk for metabolic syndrome.

Embargoed until 3 p.m. CT / 4 p.m. ET Wednesday, Sept. 6, 2017

DALLAS, Sept. 6, 2017 — African-American teens who lived through the Great Recession of 2007-2009 may have higher risk of metabolic syndrome, a common cluster of risk factors for heart disease and diabetes, according to new research in Journal of the American Heart Association, the Open Access Journal of the American Heart Association/American Stroke Association.

Researchers studied 328 African-Americans who had experienced the Great Recession of 2007-2009 as 16- and 17-year-olds living in nine rural counties in Georgia with high poverty rates and high rates of death from cardiovascular disease.

From late 2007 to mid-2009, the United States experienced the largest economic recession since the Great Depression of 1929 that lasted through most of the 1930s. Rural African-American communities in the Southeast, already in financially precarious situations, were among the hardest hit, and many have yet to recover the lost jobs, social services and wealth.

The study determined whether these teens developed a cluster of risk factors that raise the risk of heart attack, stroke and diabetes – known as metabolic syndrome by age 25. Metabolic syndrome includes a large waistline, high triglyceride (blood fat) levels, low HDL (the “good cholesterol”) levels, high blood pressure and high blood sugar when fasting.

“In previous studies, heart attack and stroke rates have gone up in older adults during economic downturns, particularly when the labor market is bad,” said Gregory E. Miller, Ph.D., lead study author and professor of psychology and a faculty fellow at Northwestern University’s Institute for Policy Research in Evanston, Illinois. “But few, if any, studies have looked at how these same economic forces affect cardiovascular risk in younger people.”

Researchers categorized study participants into three different groups based on their family’s economic path from before and after the Great Recession: those whose family incomes were low but stable (Stable Low Income), those whose low family income dropped during the recession (Downward Mobility) and those already living in poverty who became deeply impoverished (Deepening Poverty). A few families experienced upward mobility, but their numbers were too small to draw conclusions.

Then almost a decade later, when the participants were 25-26 years old, they studied rates of metabolic syndrome and found that it differed in the groups. Metabolic syndrome was diagnosed in:

  • 10.4 percent of those in the Stable Low-Income group,
  • 21.8 percent of those in the Downward Mobility group, and
  • 27.5 percent in the Deeping Poverty group.

Researchers said although metabolic syndrome is defined somewhat differently by medical groups, study results remained consistent across three definitions.

The study was not designed to determine why metabolic syndrome was higher in some groups than others, but authors speculate that the more a family’s financial situation deteriorated, the less likely the teenagers were to eat healthy and exercise. Authors also believe stress played a role in the findings.

Researchers said they were surprised that the percentage of metabolic syndrome among the Stable Low-Income group was so low. Nationally, they wrote, about 18 percent of 20- to 29-year-olds are estimated to have metabolic syndrome. They noted that even those in the Downward Mobility group were only slightly more likely to have metabolic syndrome than the national average.

“It may be that there were ‘protective resources’ that these teenagers drew upon that insulated them from the larger economic forces,” Miller said. “Strong family relationships, community ties through churches and schools are a real strength that may have offset some of the risk that came with the Great Recession.”

He added that pediatricians and primary care providers may have helped. “They may have looked at the broader social situations and said to their patients, ‘You’ve had this great stressor in your life, so now’s the time to take stock of our lifestyle and make sure you’re eating well and exercising regularly.’”

Study limitations include the fact that participants were not tested for metabolic syndrome before the Great Recession, and study findings may not be generalizable to teenagers living elsewhere who made the transition to adulthood during the same time.

Co-authors are Edith Chen, Ph.D.; Tianyi Yu, Ph.D.; and Gene H. Brody, Ph.D.  Author disclosures are on the manuscript.

The National Institute of Child Health and Human Development, the National Heart, Lung, and Blood Institute and the National Institute on Drug Abuse supported the study.

Additional Resources:

###

Statements and conclusions of study authors published in American Heart Association scientific journals are solely those of the study authors and do not necessarily reflect the association’s policy or position. The association makes no representation or guarantee as to their accuracy or reliability. The association receives funding primarily from individuals; foundations and corporations (including pharmaceutical, device manufacturers and other companies) also make donations and fund specific association programs and events. The association has strict policies to prevent these relationships from influencing the science content. Revenues from pharmaceutical and device corporations and health insurance providers are available at www.heart.org/corporatefunding.

About the American Heart Association

The American Heart Association is devoted to saving people from heart disease and stroke – the two leading causes of death in the world. We team with millions of volunteers to fund innovative research, fight for stronger public health policies and provide lifesaving tools and information to prevent and treat these diseases. The Dallas-based association is the nation’s oldest and largest voluntary organization dedicated to fighting heart disease and stroke. To learn more or to get involved, call 1-800-AHA-USA1, visit heart.org or call any of our offices around the country. Follow us on Facebook and Twitter.

For Media Inquiries and AHA/ASA Spokesperson Perspective: 214-706-1173

Karen Astle: 214-706-1392; karen.astle@heart.org

For Public Inquiries: 1-800-AHA-USA1 (242-8721)

heart.org and strokeassociation.org

 

]]>Heart NewsWed, 06 Sep 2017 20:00:08 GMTStudy Highlights: Black teens who lived through the Great Recession of 2007-2009 may have higher risk of metabolic syndrome, a cluster of several heart disease and diabetes risk factors. Black teens whose families were already in poverty when the Great Recession hit and became more deeply impoverished during that time were at highest risk for metabolic syndrome. http://newsroom.heart.org/news/black-teens-from-great-recession-may-have-higher-risk-factors-for-heart-disease-diabetesWed, 06 Sep 2017 20:00:00 GMT
Study Highlights

  • Risk of blood clots in the veins was associated with height, with the lowest risk in participants who were five feet tall or shorter.
  • The exact association between height and clots in veins remains to be determined.

Embargoed until 3 p.m. CT / 4 p.m. ET Tuesday, September 5, 2017

DALLAS, September 5, 2017 – The taller you are, the more likely you may be to develop blood clots in the veins, according to new research in the American Heart Association journal Circulation: Cardiovascular Genetics.

In a study of more than two million Swedish siblings, researchers found that the risk of venous thromboembolism – a type of blood clot that starts in a vein – was associated with height, with the lowest risk being in shorter participants.

They also found:

  • For men shorter than 5’3”, the risk for venous thromboembolism dropped 65 percent when compared to the men 6’2” or taller.
  • For women, shorter than 5’1” who were pregnant for the first time, the risk for venous thromboembolism dropped 69 percent, compared to women that were 6 feet or taller.

“Height is not something we can do anything about,” said lead researcher Bengt Zöller, M.D., Ph.D., associate professor at Lund University and Malmö University Hospital in Malmö, Sweden. “However, the height in the population has increased, and continues increasing, which could be contributing to the fact that the incidence of thrombosis has increased.”

The CDC estimates venous thromboembolism affects up to 600,000 Americans every year, making it the third leading cause of heart attack and stroke. The most common triggers are surgery, cancer, immobilization and hospitalization. In women, pregnancy and use of hormones like oral contraceptive or estrogen for menopause symptoms are also important triggers.

Zöller said gravity may influence the association between height and venous thromboembolism risk. “It could just be that because taller individuals have longer leg veins there is more surface area where problems can occur,” Zöller said. “There is also more gravitational pressure in leg veins of taller persons that can increase the risk of blood flow slowing or temporarily stopping.”

One caution is that researchers didn’t have access to data for childhood and parent lifestyle factors such as smoking, diet and physical activity. In addition, the study consisted primarily of Swedish people and may not be translatable to the U.S. population. Although, researchers note, the Swedish population nowadays is as ethnically diverse as the U.S. population.

“I think we should start to include height in risk assessment just as overweight, although formal studies are needed to determine exactly how height interacts with inherited blood disorders and other conditions,” Zöller said.

Co-authors are Jinguang Ji, M.D., Ph.D.; Jan Sundquist, M.D., Ph.D., and Kristina Sundquist, M.D., Ph.D. Author disclosures are on the manuscript.

This study was supported by the Swedish Heart-Lung Foundation, the Swedish Research Council, the Swedish Council for Working Life and Social Research and the Swedish Freemasons’ Foundation, ALF-funding (Academic Learning and Research grants) from faculty of Medicine, Lund University and Region Skåne.

Additional Resources:

###

Statements and conclusions of study authors published in American Heart Association scientific journals are solely those of the study authors and do not necessarily reflect the association’s policy or position. The association makes no representation or guarantee as to their accuracy or reliability. The association receives funding primarily from individuals; foundations and corporations (including pharmaceutical, device manufacturers and other companies) also make donations and fund specific association programs and events. The association has strict policies to prevent these relationships from influencing the science content. Revenues from pharmaceutical and device corporations and health insurance providers are available at www.heart.org/corporatefunding.

About the American Heart Association

The American Heart Association is devoted to saving people from heart disease and stroke – the two leading causes of death in the world. We team with millions of volunteers to fund innovative research, fight for stronger public health policies and provide lifesaving tools and information to prevent and treat these diseases. The Dallas-based association is the nation’s oldest and largest voluntary organization dedicated to fighting heart disease and stroke. To learn more or to get involved, call 1-800-AHA-USA1, visit heart.org or call any of our offices around the country. Follow us on Facebook and Twitter.

For Media Inquiries and AHA/ASA Spokesperson Perspective: 214-706-1173

Akeem Ranmal: 214-706-1755; akeem.ranmal@heart.org  

For Public Inquiries: 1-800-AHA-USA1 (242-8721)

heart.org and strokeassociation.org

 

]]>Heart NewsTue, 05 Sep 2017 20:00:07 GMTStudy Highlights: Risk of blood clots in the veins was associated with height, with the lowest risk in participants who were five feet tall or shorter. The exact association between height and clots in veins remains to be determined. http://newsroom.heart.org/news/can-height-increase-risk-for-blood-clots-in-veinsTue, 05 Sep 2017 20:00:00 GMT
Study Highlights

  • Awareness, treatment and control of high blood pressure is significantly lower in young adults compared to middle-aged and older adults.
  • Young men lag behind young women in all these areas related to high blood pressure.
  • Researchers urge all adults to check their blood pressure frequently.

Embargoed 3 p.m. CT / 4 p.m. ET Monday, Aug. 28, 2017

DALLAS, Aug. 28, 2017 – Young adults, particularly men, lag behind middle-aged and older adults in awareness and treatment of high blood pressure, putting this population at an increased risk for heart attack and stroke, according to new research in the American Heart Association’s journal Hypertension.

High blood pressure is a leading risk factor for heart attack and stroke and is also a significant public health burden, costing the United States about $110 billion in direct and indirect costs in 2015, according to American Heart Association estimates. American Heart Association guidelines define blood pressure as normal at less than 120/80 and high blood pressure as 140/90 or above.

“While hypertension awareness, treatment and control have improved overall since the early 2000s, all three remain worse in young adults – those aged 18-39,” said senior study author Andrew Moran, M.D., M.P.H., an assistant professor at Columbia University Medical Center in New York.

The study, based on 1999-2014 data taken from more than 41,000 people who participated in eight national health surveys, examined the prevalence and management of high blood pressure among adults.

Among the researchers’ key findings:

  • Only half of the 6.7 million young adults with high blood pressure in 2013-2014 received treatment and only 40 percent got their blood pressure under control.
  • Among young men, rates of awareness, treatment and control were lower compared to young women (68.4 percent versus 86 percent for awareness; 43.7 percent versus 61.3 percent for treatment; and 33.7 percent vs. 51.8 percent for control).
  • Nearly three-quarters of young adults who had high blood pressure were obese compared with 57 percent of middle-aged adults and 42 percent of older adults, suggesting that young adults with high blood pressure are more than twice as likely to be obese.

Researchers noted young women are more likely to have their blood pressure checked due to more frequent healthcare visits like gynecological exams or prenatal care.

The prevalence of prehypertension (readings from 120-139/80-89), was significantly higher among young men (33.6 percent) than young women (12.8 percent). According to the American Heart Association, people with pre-hypertension are likely to develop high blood pressure unless steps are taken to control it.

“Our study identified shortfalls in high blood pressure screening and management among young adults and especially young adult males,” said lead study author Yiyi Zhang, Ph.D., associate research scientist at Columbia University Medical Center in New York. “The first step for young adults is to have their blood pressure measured, whether in a doctor’s office, pharmacy or other place in their community. Young adults with consistently high blood pressure need a link to clinical care to verify the diagnosis and receive regular monitoring and possibly treatment.”

This study emphasizes the need to focus on early hypertension prevention and management in young adults. It also highlights the importance of addressing policy issues related to healthcare access and utilization.

Recognizing the need and importance of blood pressure control, in 2015 the American Heart Association and the American Medical Association began collaborating to get more people appropriately treated to control. Target:BP is a recognition program that urges medical practices, hospitals and health service organizations to reach and sustain a blood pressure control rate of 70 percent or higher among the high blood pressure patients they serve.

Author disclosures are on the manuscript. The National Institutes of Health funded the study.

Additional Resources:

###

Statements and conclusions of study authors published in American Heart Association scientific journals are solely those of the study authors and do not necessarily reflect the association’s policy or position. The association makes no representation or guarantee as to their accuracy or reliability. The association receives funding primarily from individuals; foundations and corporations (including pharmaceutical, device manufacturers and other companies) also make donations and fund specific association programs and events. The association has strict policies to prevent these relationships from influencing the science content. Revenues from pharmaceutical and device corporations and health insurance providers are available at www.heart.org/corporatefunding.

About the American Heart Association

The American Heart Association is devoted to saving people from heart disease and stroke – the two leading causes of death in the world. We team with millions of volunteers to fund innovative research, fight for stronger public health policies and provide lifesaving tools and information to prevent and treat these diseases. The Dallas-based association is the nation’s oldest and largest voluntary organization dedicated to fighting heart disease and stroke. To learn more or to get involved, call 1-800-AHA-USA1, visit heart.org or call any of our offices around the country. Follow us on Facebook and Twitter.

For Media Inquiries and AHA/ASA Spokesperson Perspective: 214-706-1173

Bridgette McNeill: 214-706-1135; bridgette.mcneill@heart.org

For Public Inquiries: 1-800-AHA-USA1 (242-8721)

heart.org and strokeassociation.org

 

 

]]>Heart NewsStroke NewsMon, 28 Aug 2017 20:00:10 GMTStudy Highlights: Awareness, treatment and control of high blood pressure is significantly lower in young adults compared to middle-aged and older adults. Young men lag behind young women in all these areas related to high blood pressure. Researchers urge all adults to check their blood pressure frequently. http://newsroom.heart.org/news/young-adults-especially-men-fall-behind-in-high-blood-pressure-treatment-and-controlMon, 28 Aug 2017 20:00:00 GMT
Study Highlights

  • A pattern of brain activity that occurs during psychological stress may predict bodily reactions, such as surges in our blood pressure, that increase risk for cardiovascular disease.
  • People who have exaggerated responses to stressors, like large rises in blood pressure or heart rate, are at greater risk of developing hypertension and premature death from cardiovascular disease, researchers say.

Embargoed until 3 p.m. CT / 4 p.m. ET Wednesday, Aug. 23, 2017

DALLAS, Aug. 23, 2017 — The brain may have a distinctive activity pattern during stressful events that predicts bodily reactions, such as rises in blood pressure that increase risk for cardiovascular disease, according to new proof-of-concept research in the Journal of the American Heart Association, the Open Access Journal of the American Heart Association/American Stroke Association.

The new research, the largest brain-imaging study of cardiovascular stress physiology to date, introduced a brain-based explanation of why stress might influence a person’s heart health.   

“Psychological stress can influence physical health and risk for heart disease, and there may be biological and brain-based explanations for this influence,” said Peter Gianaros, Ph.D., the study’s senior author and psychology professor at the University of Pittsburgh in Pennsylvania.

To help understand the brain-body link between stress and health, researchers conducted mental stress tests and monitored blood pressure and heart rates during an MRI procedure. The mental tests were designed to create a stressful experience by having research volunteers receive negative feedback while they were making time-pressured responses to computer challenges.

Research participants – 157 men and 153 women – were 30 to 51 years old and part of the Pittsburgh Imaging Project, an ongoing study of how the brain influences cardiovascular disease risk. As expected, the mental stress tests increased blood pressure and heart rate in most of the volunteers compared to a non-stress baseline period.

Using machine-learning, researchers determined that a specific brain activity pattern reliably predicted the size of the volunteers’ blood pressure and heart rate reactions to the mental stress tests.

The brain areas that were especially predictive of stress-related cardiovascular reactions included those that determine whether information from the environment is threatening and that control the heart and blood vessels through the autonomic nervous system.

The study was based on a group of middle-aged healthy adults at low levels of risk for heart disease, so the findings may not be applicable to patients with existing heart disease. Also, brain imaging does not allow researchers to draw conclusions about causality.

“This kind of work is proof-of-concept, but it does suggest that, in the future, brain imaging might be a useful tool to identify people who are at risk for heart disease or who might be more or less suited for different kinds of interventions, specifically those that might be aimed at reducing levels of stress,” Gianaros said. “It’s the people who show the largest stress-related cardiovascular responses who are at the greatest risk for poor cardiovascular health and understanding the brain mechanisms for this may help to reduce their risk.”

Co-authors are Lei Sheu, Ph.D.; Fatma Uyar, Ph.D.; Jayanth Koushik, B.S.; J. Richard Jennings, Ph.D.; Tor Wager, Ph.D.; Aarti Singh, Ph.D.; and Timothy Verstynen, Ph.D. Author disclosures are on the manuscript.

The National Institutes of Health and the National Science Foundation funded the study.

Additional Resources:

###

Statements and conclusions of study authors published in American Heart Association scientific journals are solely those of the study authors and do not necessarily reflect the association’s policy or position. The association makes no representation or guarantee as to their accuracy or reliability. The association receives funding primarily from individuals; foundations and corporations (including pharmaceutical, device manufacturers and other companies) also make donations and fund specific association programs and events. The association has strict policies to prevent these relationships from influencing the science content. Revenues from pharmaceutical and device corporations and health insurance providers are available at www.heart.org/corporatefunding.

About the American Heart Association

The American Heart Association is devoted to saving people from heart disease and stroke – the two leading causes of death in the world. We team with millions of volunteers to fund innovative research, fight for stronger public health policies, and provide lifesaving tools and information to prevent and treat these diseases. The Dallas-based association is the nation’s oldest and largest voluntary organization dedicated to fighting heart disease and stroke. To learn more or to get involved, call 1-800-AHA-USA1, visit heart.org or call any of our offices around the country. Follow us on Facebook and Twitter.

For Media Inquiries and AHA/ASA Spokesperson Perspective: 214-706-1173

Akeem Ranmal: 214-706-1755; akeem.ranmal@heart.org  

For Public Inquiries: 1-800-AHA-USA1 (242-8721)

heart.org and strokeassociation.org

 

]]>Heart NewsWed, 23 Aug 2017 20:00:09 GMTStudy Highlights: A pattern of brain activity that occurs during psychological stress may predict bodily reactions, such as surges in our blood pressure, that increase risk for cardiovascular disease. People who have exaggerated responses to stressors, like large rises in blood pressure or heart rate, are at greater risk of developing hypertension and premature death from cardiovascular disease, researchers say. http://newsroom.heart.org/news/brain-activity-may-be-predictor-of-stress-related-cardiovascular-riskWed, 23 Aug 2017 20:00:00 GMT
Study Highlights

  • Low-income patients with high blood pressure whose healthcare providers did not use collaborative communication styles or ask about social issues, such as employment and housing, were less likely to take their blood pressure medications as directed.
  • Low-income black patients were least likely to take their medication when social issues weren’t discussed.

Embargoed until 3 p.m. CT / 4 p.m. ET Tuesday, August 22, 2017

DALLAS, August 22, 2017 — The key to getting low-income patients to take their blood pressure medications as prescribed may be as simple as a conversation. Low-income patients with high blood pressure were less likely to take their medications as directed when their healthcare providers did not use a collaborative communication style or ask them about social issues such as employment, housing and partner relationships, according to new research in the American Heart Association’s journal Circulation: Quality and Outcomes.

Patients not taking high blood pressure medication as directed plays a major role in the continued problem of poorly controlled high blood pressure, a significant risk factor for heart attacks and strokes. Researchers found that patients were three times less likely to take their high blood pressure medications when their providers did not possess a collaborative communication style such as asking open-ended questions and checking their understanding of instructions. Patients were also six times less likely to take their medications as prescribed when a healthcare provider did not ask them about social issues such as employment, housing and partner relationships.

“When healthcare providers ask patients about life challenges or take the time to check their patient’s understanding of instructions, it signals that their healthcare provider genuinely cares about them and provides the motivation and confidence to manage their health issues on their own,” said Antoinette Schoenthaler, Ed.D., lead author for the study and an associate professor of medicine at NYU School of Medicine in New York City.

The researchers audiotaped interactions between 92 patients and 27 providers over a three-month period from three practices that serve a multi-ethnic, low-income population in New York City. One office visit for each patient was audiotaped.

The majority of the patients were black, unemployed and reported some college education. Fifty-eight percent of patients were women and most were seeing the same provider for at least one year. The providers (56 percent white; 67 percent women) have been in practice for an average of 5.8 years. The researchers measured whether patients took their medications during the three-month study period through the use of an electronic monitoring device that recorded the time and date each time they opened the pill bottle.

The researchers found striking differences in medication adherence between the black and white patients. Overall, black patients were more likely to have poor adherence to their blood pressure medications compared to white patients. Moreover, compared to the overall patient population, non-adherence was more pronounced with black patients when social issues were not discussed (eight times less likely to take medication as prescribed compared to six).

“Healthcare providers should talk to patients about the things that get in the way of taking their medication, such as relationship status, employment and housing. Unemployment, for example, affects whether patients can afford medication, which is a primary risk factor for non-adherence. If these issues go undiscussed, healthcare providers may never figure out why patients are not taking their medications,” said Schoenthaler.

She suggested healthcare providers work with community health workers, nurses or medical assistants, to help identify resources for patients who have difficulty taking their medications.

Co-authors are George J. Knafl, Ph.D., Kevin Fiscella, M.D. and Gbenga Ogedegbe, M.D.Author disclosures are on the manuscript.

The National Heart, Lung, and Blood Institute funded the study.

Additional Resources:

###

Statements and conclusions of study authors published in American Heart Association scientific journals are solely those of the study authors and do not necessarily reflect the association’s policy or position. The association makes no representation or guarantee as to their accuracy or reliability. The association receives funding primarily from individuals; foundations and corporations (including pharmaceutical, device manufacturers and other companies) also make donations and fund specific association programs and events. The association has strict policies to prevent these relationships from influencing the science content. Revenues from pharmaceutical and device corporations and health insurance providers are available at www.heart.org/corporatefunding.

About the American Heart Association

The American Heart Association is devoted to saving people from heart disease and stroke – the two leading causes of death in the world. We team with millions of volunteers to fund innovative research, fight for stronger public health policies and provide lifesaving tools and information to prevent and treat these diseases. The Dallas-based association is the nation’s oldest and largest voluntary organization dedicated to fighting heart disease and stroke. To learn more or to get involved, call 1-800-AHA-USA1, visit heart.org or call any of our offices around the country. Follow us on Facebook and Twitter.

For Media Inquiries and AHA/ASA Spokesperson Perspective: (214) 706-1173

Darcy Spitz; (212) 878-5940; darcy.spitz@heart.org

For Public Inquiries: (800)-AHA-USA1 (242-8721)

heart.org and strokeassociation.org

]]>Heart NewsStroke NewsTue, 22 Aug 2017 20:00:08 GMTStudy Highlights: Low-income patients with high blood pressure whose healthcare providers did not use collaborative communication styles or ask about social issues, such as employment and housing, were less likely to take their blood pressure medications as directed. Low-income black patients were least likely to take their medication when social issues weren’t discussed. http://newsroom.heart.org/news/low-income-patients-more-likely-to-take-blood-pressure-medication-when-doctor-involves-them-in-conversationTue, 22 Aug 2017 20:00:00 GMT
Study Highlights

  • Exposure to fine particulate matter via air pollution, led to increases in stress hormones and, in a study of healthy college students in China.
  • Negative effects of pollution exposure decreased after using indoor air purifiers over a 9-day period.

Embargoed until 3 p.m. CT / 4 p.m. ET Monday, Aug. 14, 2017

DALLAS, Aug. 14, 2017 — Exposure to high levels of air pollution increased stress hormone levels and negative metabolic changes in otherwise healthy, young adults in a recent study conducted in China. Air purifiers appeared to lessen the negative effects, according to new research published in the American Heart Association’s journal Circulation.

Researchers focused on fine particulate matter (PM2.5) – a component of air pollution emitted from vehicles, factories, power plants, fires and smoking – because many studies have suggested this type of major air pollutant might lead to cardiovascular and metabolic health consequences, according to Haidong Kan, M.D., Ph.D., study author and professor of environmental health sciences at Fudan University in Shanghai, China.

However, the biological mechanisms linking air pollution to cardiovascular risk are unclear. In this study, the first of its kind, researchers used “metabolomics” – a method that could reflect how glucose, amino acids, fatty acids and lipids are metabolized – to get a snapshot of the chemical processes by which cells produce the substances and energy needed to sustain life.

Researchers recruited 55 healthy, young college students, who received alternate treatments of real and sham air purification in random orders in their dormitory rooms.

Researchers measured indoor and outdoor fine particulate matter levels during the study, and at certain points did health tests and collected blood serum and urine samples to analyze the students’ metabolites, inflammation and oxidative stress biomarkers. They looked for differences in blood serum metabolites, biomarkers and blood pressures with increasing exposure to fine particulate matter.

Researchers found:

  • Notable changes in 97 blood serum metabolites after fine particulate matter exposure.
  • An average 82 percent lower level of indoor fine particulate matter with air purifiers versus sham purifiers.
  • Short-term reductions in stress hormone levels after air purifiers were used.
  • After 24-hours with real air purifiers in use, exposure levels for fine particulate matter were in the safe range per World Health Organization.

Higher fine particulate matter exposure was also associated with increases in stress hormone levels, which are believed to induce high blood pressure, inflammatory and metabolic effects in the body, Kan said.

Fine particulate matter exposure impacted metabolism of glucose, amino acids, fatty acids and lipids. These changes, along with the significantly higher blood pressure, insulin resistance and biomarkers of inflammation and oxidative stress found among people exposed to higher levels, could be partly responsible for the adverse cardiovascular effects caused by air pollution exposure, researchers said.

“Levels of stress hormones, systolic blood pressure and biomarkers of oxidative stress and inflammation were significantly lower when using real air purifiers,” Kan said. “Although we found significant health benefits with air purifiers, the actual health protection people could get from air purifiers in real living conditions is still not well-determined.”

This was also a small study and whether the results translate to other countries remains to be seen, because air pollution levels are much higher in urban China than in the United States or Europe. Nevertheless, the study highlights air pollution’s potential impact on human health in more ways than we currently know, Kan said.

“Future studies should examine whether the health benefits from short-term air purification can improve long-term health, and whether these findings are also found in people who live in low pollution areas,” Kan said. The current study only focused on one particulate matter size found in pollution.

Co-authors are Huichu Li, M.S.; Jing Cai, Ph.D.; Renjie Chen, Ph.D.; Zhuohui Zhao, Ph.D.; Zhekang Ying, Ph.D.; Lin Wang, Ph.D.; Jianmin Chen, Ph.D.; Ke Hao, Sc.D.; Patrick L. Kinney, Sc.D. and Honglei Chen, M.D. Ph.D. Author disclosures are on the manuscript.

The National Natural Science Foundation of China, Public Welfare Research Program of National Health and Family Planning Commission of China, Shanghai 3-Year Public Health Action Plan, Cyrus Tang Foundation and China Medical Board Collaborating Program funded the study.

Additional Resources:

###

Statements and conclusions of study authors published in American Heart Association scientific journals are solely those of the study authors and do not necessarily reflect the association’s policy or position. The association makes no representation or guarantee as to their accuracy or reliability. The association receives funding primarily from individuals; foundations and corporations (including pharmaceutical, device manufacturers and other companies) also make donations and fund specific association programs and events. The association has strict policies to prevent these relationships from influencing the science content. Revenues from pharmaceutical and device corporations and health insurance providers are available at www.heart.org/corporatefunding.

About the American Heart Association

The American Heart Association is devoted to saving people from heart disease and stroke –  the two leading causes of death in the world. We team with millions of volunteers to fund innovative research, fight for stronger public health policies, and provide lifesaving tools and information to prevent and treat these diseases. The Dallas-based association is the nation’s oldest and largest voluntary organization dedicated to fighting heart disease and stroke. To learn more or to get involved, call 1-800-AHA-USA1, visit heart.org or call any of our offices around the country. Follow us on Facebook and Twitter.

For Media Inquiries and AHA/ASA Spokesperson Perspective: 214-706-1173

Karen Astle: 214-706-1392; karen.astle@heart.org

For Public Inquiries: 800-AHA-USA1 (242-8721)

heart.org and strokeassociation.org

]]>Heart NewsWed, 16 Aug 2017 21:21:40 GMTStudy Highlights: Exposure to fine particulate matter via air pollution, led to increases in stress hormones and, in a study of healthy college students in China. Negative effects of pollution exposure decreased after using indoor air purifiers over a 9-day period. http://newsroom.heart.org/news/air-pollution-linked-to-cardiovascular-disease-air-purifiers-may-lessen-impactMon, 14 Aug 2017 20:00:00 GMT
Study Highlights

  • Children from socially and economically disadvantaged families and neighborhoods appear more likely to have thicker carotid artery walls, which in middle-aged and older adults has been associated with higher risk for heart attack and stroke.
  • The socioeconomic position of a child’s family was more strongly associated with thicker carotid artery walls than living in a disadvantaged neighborhood.

Embargoed until 3 p.m. CT / 4 p.m. ET Wednesday, Aug. 9, 2017

DALLAS, Aug. 9, 2017 — Children from socially and economically disadvantaged families and neighborhoods appear more likely to have thicker carotid artery walls, which in adults may indicate higher risk for heart attack and stroke in later life, according to new research in Journal of the American Heart Association, the Open Access Journal of the American Heart Association/American Stroke Association.

The carotid arteries supply blood to the brain. An ultrasound test of the arteries’ inner layers, the intima and media, may detect the early development of atherosclerosis, or “hardening of the arteries,” which underlies the development of cardiovascular disease later in life.

“We know that socioeconomically disadvantaged people are at greater risk of health problems, including more cardiovascular disease earlier in life, and we also know that atherosclerosis is a life-long process that starts in childhood,” said David P. Burgner, Ph.D., senior study author and senior research fellow at Murdoch Children’s Research Institute in Melbourne, Australia. “For this study, we wanted to determine if there is an association between socioeconomic position and the thickness of the carotid artery wall in mid-childhood.”

Researchers analyzed both family and neighborhood socioeconomic position data from 1,477 Australian families. Socioeconomic measures included income, education and the occupation of parents, as well as the relative socioeconomic status of the immediate neighborhood. Between the ages of 11 and 12, the children’s right carotid artery was imaged and maximum carotid intima-media thickness measured.

The study found:

  • Both family and neighborhood socioeconomic position were associated with carotid artery inner layer thickness, but the family association was stronger.
  • Children whose family socioeconomic position was in the bottom fourth (most disadvantaged) at age 11-12 were 46 percent more likely to have thicker carotid measurement, i.e. above the 75th percentile.
  • Socioeconomic position as early as age 2-3 years was linked to thickness in carotid artery measurements at age 11-12.

Researchers said that when they considered traditional cardiovascular risk factors, including body weight, blood pressure and exposure to second-hand smoke, their findings did not change.

“It is surprising to see that these traditional risk factors do not appear responsible for our findings,” said Richard S. Liu, M.B.B.S., lead author, resident medical officer and Ph.D. student at the Murdoch Children’s Research Institute. “There’s a suggestion that there may be additional factors driving this association.”

Based on their other research studies, the authors propose that infection and inflammation may be among the additional underlying factors. Infection, which leads to inflammation, is more common among those who are socioeconomically disadvantaged, they noted.

“This doesn’t mean that body weight and blood pressure aren’t important — they are — but there appear to be additional factors that contribute to cardiovascular disease risk beyond the traditional factors,” Burgner said. “So, there may be multiple opportunities for early intervention to prevent cardiovascular disease.”

The authors wrote that, given the link between socioeconomic position in infancy and carotid artery measurements at mid-childhood, it may be that cardiovascular disease risk begins before a baby is born. “Reducing social inequality and poverty before birth, as well as in early childhood, is likely to have a significant impact on later cardiovascular disease,” Liu said.

“Every child needs and deserves the opportunity to grow up healthy,” said Clyde Yancy, M.D., American Heart Association past president and chief of cardiology at Northwestern University in Chicago. “Fortunately, we have the tools to improve heart health across the lifespan by ensuring every child has healthy foods to eat and safe places to be active. Community leaders need to focus on giving kids a healthy start from birth, healthy schools as they grow up, and healthy communities for families to thrive.”

Because this is an observational study, a cause-and-effect association between socioeconomic position and carotid IMT cannot be proved. It is also not yet known whether thicker carotid arteries in mid-childhood are linked to cardiovascular risk in adulthood. All study participants were Australian, which may limit application of findings to other populations.

Other co-authors are Fiona K Mensah, Ph.D.; John Carlin, Ph.D.; Ben Edwards, Ph.D.; Sarath Ranganathan, Ph.D.; Michael Cheung, M.D.; Terence Dwyer, M.D.; Richard Saffery, Ph.D.; Costan G. Magnussen, Ph.D.; Markus Juonala, Ph.D. and Melissa Wake, M.D. Author disclosures are on the manuscript.

The study was funded by the National Health and Medical Research Council of Australia, The Royal Children’s Hospital Foundation, Murdoch Children’s Research Institute, The University of Melbourne, National Heart Foundation of Australia, Financial Markets Foundation for Children, and Victorian Deaf Education Institute.

Additional Resources:

###

Statements and conclusions of study authors published in American Heart Association scientific journals are solely those of the study authors and do not necessarily reflect the association’s policy or position. The association makes no representation or guarantee as to their accuracy or reliability. The association receives funding primarily from individuals; foundations and corporations (including pharmaceutical, device manufacturers and other companies) also make donations and fund specific association programs and events. The association has strict policies to prevent these relationships from influencing the science content. Revenues from pharmaceutical and device corporations and health insurance providers are available at www.heart.org/corporatefunding.

About the American Heart Association

The American Heart Association is devoted to saving people from heart disease and stroke – the two leading causes of death in the world. We team with millions of volunteers to fund innovative research, fight for stronger public health policies, and provide lifesaving tools and information to prevent and treat these diseases. The Dallas-based association is the nation’s oldest and largest voluntary organization dedicated to fighting heart disease and stroke. To learn more or to get involved, call 1-800-AHA-USA1, visit heart.org or call any of our offices around the country. Follow us on Facebook and Twitter.

For Media Inquiries and AHA/ASA Spokesperson Perspective: 214-706-1173

Karen Astle: 214-706-1392; karen.astle@heart.org

For Public Inquiries: 1-800-AHA-USA1 (242-8721)

heart.org and strokeassociation.org

]]>Heart NewsStroke NewsWed, 09 Aug 2017 20:00:09 GMTStudy Highlights: Children from socially and economically disadvantaged families and neighborhoods appear more likely to have thicker carotid artery walls, which in middle-aged and older adults has been associated with higher risk for heart attack and stroke. The socioeconomic position of a child’s family was more strongly associated with thicker carotid artery walls than living in a disadvantaged neighborhood. http://newsroom.heart.org/news/disadvantaged-kids-may-be-at-higher-risk-for-heart-disease-later-in-lifeWed, 09 Aug 2017 20:00:00 GMT
Study Highlights

  • In a study of older Japanese people, large variations in blood pressure readings during home monitoring were associated with a higher risk of all types of dementia, including Alzheimer’s disease.
  • The link between daily blood pressure fluctuations and dementia were noted whether participants had normal or high blood pressure.

Embargoed until 3 p.m. CT / 4 p.m. ET Monday, Aug. 7, 2017

DALLAS, Aug. 7, 2017 — Whether or not you have high blood pressure, your risk of dementia may be higher if your pressure varies a lot from day to day, according to new research in the American Heart Association’s journal Circulation.

“Home monitoring of blood pressure may be useful to assess the future risk of dementia,” said lead study author Tomoyuki Ohara, M.D., Ph.D., an assistant professor of neuropsychiatry at the Graduate School of Medical Sciences at Kyushu University in Fukuoka City, Japan.

Previous studies reported a heightened risk of cognitive impairment and dementia in people with large variations in blood pressure from one doctor visit to another, but this is the first study to use home monitoring to examine the association between blood pressure variability and dementia risk.

Home monitoring may be more reliable than office measurements because of the “white-coat” effect, in which some people have higher blood pressure in the doctor’s office than they do at home.

Researchers asked more than 1,600 Japanese adults without dementia (average age 71; 56 percent female) to measure their blood pressure at home for one month. On average participants measured their blood pressure three times each morning prior to eating breakfast or taking medication. Participants included both those with normal and high blood pressure. About 4 in 10 were taking medication for high blood pressure. Researchers reviewed the month of home blood pressure readings, conducted cognitive testing to uncover the development of dementia and reviewed records for the occurrence of stroke.

During the five-year follow-up, 134 subjects developed Alzheimer’s disease and 47 developed vascular dementia, which results from diminished blood flow to the brain and is often related to the occurrence of small strokes.

Compared with participants who had the most stable blood pressure, and after adjusting for other dementia risk factors and the average blood pressure levels themselves, those with the highest variability in systolic (higher number) blood pressure were:

  • more than twice as likely to develop any type of dementia (2.27 times) or Alzheimer’s disease (2.2 times), and
  • nearly three times more likely to develop vascular dementia (2.79 times).

In addition, among participants with greater blood pressure variability, higher systolic blood pressure further increased the risk of vascular dementia but did not change the heightened risk of Alzheimer’s disease.

“Further studies are needed to clarify whether day-to-day blood pressure variation is an indicator of future dementia, or whether it might be a target for interventions aimed at preventing dementia,” Ohara said. “Blood pressure variation may indicate high blood pressure that is inadequately treated, but other factors, such as mental or physical stress, sleep deprivation, an irregular lifestyle, or damage to nerves that control involuntary bodily functions, can also contribute.”

The American Heart Association recommends home monitoring for all people with high blood pressure to help the healthcare provider determine whether treatments are working.

“This research adds to the evidence that blood pressure fluctuations can have serious consequences and highlights the importance of getting frequent, accurate measurements to provide patients with the best treatment plan to prevent those consequences,” said American Heart Association volunteer Mary Ann Bauman, M.D.

“Home blood pressure monitoring is becoming more important for diagnosing and managing high blood pressure, thus making it vital that providers ensure their patients understand not only their numbers, but also how to use their home monitors appropriately,” said Bauman, medical director of INTEGRIS Family Care Central in Oklahoma City.

Participants in this study were part of the large, ongoing Hisayama Study, which has tracked for decades the health and cognitive performance in adult residents of a suburb of Fukuoka City, Japan. Because the study population was Japanese, the findings may not apply to a Western population or to other ethnic groups with different lifestyles or genetic backgrounds.

Co-authors are Emi Oishi, M.D.; Satoko Sakata, M.D.; Masayo Fukuhara, M.D, Ph.D.; Jun Hata, M.D., Ph.D.; Daigo Yoshida, Ph.D.; Mao Shibata, M.D., Ph.D.; Toshio Ohtsubo, M.D., Ph.D.; Takanari Kitazono, M.D., Ph.D.; Yutaka Kiyohara, M.D., Ph.D.; and Toshiharu Ninomiya, M.D., Ph.D. Author disclosures are on the manuscript.

The study was funded by the Ministry of Education, Culture, Sports, Science and Technology of Japan; the Ministry of Health, Labour and Welfare of Japan; and the Japan Agency for Medical Research and Development.

Additional Resources:

###

Statements and conclusions of study authors published in American Heart Association scientific journals are solely those of the study authors and do not necessarily reflect the association’s policy or position. The association makes no representation or guarantee as to their accuracy or reliability. The association receives funding primarily from individuals; foundations and corporations (including pharmaceutical, device manufacturers and other companies) also make donations and fund specific association programs and events. The association has strict policies to prevent these relationships from influencing the science content. Revenues from pharmaceutical and device corporations and health insurance providers are available at www.heart.org/corporatefunding.

About the American Heart Association

The American Heart Association is devoted to saving people from heart disease and stroke –  the two leading causes of death in the world. We team with millions of volunteers to fund innovative research, fight for stronger public health policies, and provide lifesaving tools and information to prevent and treat these diseases. The Dallas-based association is the nation’s oldest and largest voluntary organization dedicated to fighting heart disease and stroke. To learn more or to get involved, call 1-800-AHA-USA1, visit heart.org or call any of our offices around the country. Follow us on Facebook and Twitter.

For Media Inquiries and AHA/ASA Spokesperson Perspective: 214-706-1173

Bridgette McNeill: 214-706-1135; bridgette.mcneill@heart.org

For Public Inquiries: 800-AHA-USA1 (242-8721)

heart.org and strokeassociation.org

]]>Heart NewsStroke NewsMon, 07 Aug 2017 20:00:09 GMTStudy Highlights: In a study of older Japanese people, large variations in blood pressure readings during home monitoring were associated with a higher risk of all types of dementia, including Alzheimer’s disease. The link between daily blood pressure fluctuations and dementia were noted whether participants had normal or high blood pressure. http://newsroom.heart.org/news/fluctuations-in-home-monitored-blood-pressure-may-raise-dementia-riskMon, 07 Aug 2017 20:00:00 GMT

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Disclaimer
The American Heart Association strongly promotes knowledge and proficiency in BLS, ACLS, and PALS and has developed instructional materials for this purpose. Use of these materials in an educational course does not represent course sponsorship by the American Heart Association. Any fees charged for such a course, except a portion of fees needed for AHA course materials, do not represent income to the Association.

 

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